The Metropolitan Free Trade Zone of Quito is located in the Parish of Yarquí, within the Canton of Quito, in the province of Pichincha in Ecuador, South America. The Metrozona Free Trade Zone is accessible from the Panamerican Highway, at km. 32 on the Pifo-El Quinche road.

Metrozona S.A. is ideally located just 244 km. from the Colombian border, just 350 km. from the Amazonian port city of Puerto Orellana, and 578 km. from the Peruvian border at Huaquillas.

The current international airport in Quito is located 40 km. from Metrozona, S.A.. However, Quito's new international airport, to be in use within the next few years, will be located just 3 km. from Metrozona, S.A.